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Tools and expertise to improve the evidence base for national and international Illegal Wildlife Trade policy already exist but are underutilised. Tapping into these resources would produce substantive benefits for wildlife conservation and associated sectors, enabling governments to better meet their obligations under the Sustainable Development Goals and international biodiversity conventions. This can be achieved through enhanced funding support for inter-sectoral research collaborations, engaging researchers in priority setting and programme design, increasing developing country research capacity and engaging researchers and community voices in policy processes. This briefing, addressed to policy makers and practitioners, is part of the 2018 Evidence to Action: Research to Address Illegal Wildlife Trade event programme, organised by five of the UK’s most active IWT research institutions, to support the London 2018 IWT Conference.