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The objective of this report, Integrating Local Knowledge in Development Programming is to share knowledge of how development donors and implementing organizations leverage local knowledge to inform programming. In a recent speech at Georgetown University, United States Agency for International Development (USAID) Administrator Samantha Power said, “As Americans with a fraught history living up to our own values, we’ve got to approach this work with intention and humility. But the entire development community needs to interrogate the traditional power dynamics of donor-driven development and look for ways to amplify the local voices of those who too often have been left out of the conversation.” To that end, USAID’s Agency Knowledge Management and Organizational Learning (KMOL) function facilitated conversations with multilateral and bilateral donors and local organizations to understand how organizations define, utilize, and incorporate local knowledge into their programmatic and operational activities. Using qualitative tools to gather data for this report, the research team explored five overarching themes: 1. Local Knowledge Nomenclature and Definitions 2. Best Practices 3. Outcomes 4. Ethics and Power Dynamics 5. Challenges